| 1000041471 | Salutes Space UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000021327 | SAT4M2M GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000049724 | Seal Robotics | DE-Germany | Company | Yes | Incubatee | ESA BIC Bavaria | |
| 1000039379 | Servail GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000039413 | sewts GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000043915 | Sharpsat GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Northern Germany | |
| 1000033030 | SilentWings GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000048945 | Sitegeist GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000040841 | skailark GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000046344 | SmartAIs UG (haftungsbeschränkt) | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000036328 | Solenix Engineering GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000042080 | Spacefood UG (haft.besch.) | DE-Germany | Company | Yes | Alumnus | ESA BIC Northern Germany | |
| 1000026584 | Spacenus GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000042818 | Spaceping Technologies GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000048752 | SPARK Microgravity GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Bavaria | |
| 1000045249 | SRD Electronics UG (haftungsbeschränkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000043321 | Starflight Dynamics GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000042724 | StellarShip Labs GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000044870 | Stoffschmiede GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000032462 | Styx Neutronica GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |