| 1000043001 | DronEye | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000047021 | Duramea FlexCo | AT-Austria | Company | No | Incubatee | ESA BIC Austria | |
| 1000040897 | Dymium GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000031983 | Dynamic Space Technologies AS | NO-Norway | Company | No | Alumnus | ESA BIC Norway | |
| 1000049464 | Earthwise Dynamics Geo Environs (EDGE) | IE-Ireland | Company | Yes | Incubatee | ESA BIC Ireland | |
| 1000051905 | ECLIPSE | FR-France | Company | No | Incubatee | ESA BIC Nord France | |
| 1000044768 | ECLORE ACTUATORS SAS | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000042827 | Eco Urban Scooters Limited | IE-Ireland | Company | No | Alumnus | ESA BIC Ireland | |
| 1000045361 | ecoMorph Solutions GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000041734 | Ecosmic | NL-Netherlands | Company | No | Alumnus | ESA BIC Noordwijk | |
| 1000044332 | Ecosmic S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000049339 | ECOTEN urban comfort | CZ-Czech Republic | Company | Yes | Alumnus | ESA BIC Czech Republic | |
| 1000044508 | EDY S.r.l. | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |
| 1000038338 | egsespace s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |
| 1000031159 | EH Group Engineering AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000046299 | Einbus Oy | FI-Finland | Company | Yes | Incubatee | ESA BIC Finland | |
| 1000036979 | Ekofolio Sarl | LU-Luxembourg | Company | No | Alumnus | ESA BIC Denmark | |
| 1000028372 | ElFys Oy | FI-Finland | Company | Yes | Alumnus | ESA BIC Finland | |
| 1000037443 | Elysium Industries UG | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000048283 | EM Path | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |