| 1000042809 | Infraprint ltd | IE-Ireland | Company | Yes | Alumnus | ESA BIC Ireland | |
| 1000045043 | InnoPilot ApS | DK-Denmark | Company | No | Alumnus | ESA BIC Denmark | |
| 1000044671 | InnoShiftIng GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000040131 | INSIGHIO P.C. | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000039299 | Insolight SA | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000044654 | InSpacePropulsion Technologies GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden-Württemberg | |
| 1000044201 | INSPECTIONDRONE SRL | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000051257 | INSTRUMENTOS ROBOTICOS E INTELIGENCIA ARTIFICIAL S.L. | ES-Spain | Company | Yes | Incubatee | ESA BIC Castilla y Leon | |
| 1000020495 | Integricom Hungary Korlátolt Felelősségű Társasá | HU-Hungary | Company | Yes | Incubatee | ESA BIC Hungary | |
| 1000029389 | Intelligence on Wheels (IoW) GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000045638 | Intellmaps | CZ-Czech Republic | Company | No | Alumnus | ESA BIC Czech Republic | |
| 1000049955 | IntuitivAnalytix GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |
| 1000042371 | Inverto Earth AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000033601 | INVOLI | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000042887 | Involve Space S.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000050131 | Ionic Wind AG | CH-Switzerland | Company | No | Incubatee | ESA BIC Switzerland | |
| 1000047313 | IONION S.R.L. | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000047692 | IPAZIASPACE SRL | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000042504 | iQrypto | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000035998 | IRsweep AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |