| 1000025804 | Lacuna Space Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000050971 | Laelaps AI Ltd | GB-United Kingdom | Company | No | Incubatee | ESA BIC UK | |
| 1000048817 | Lagertha LTD | IE-Ireland | Company | No | Incubatee | ESA BIC Ireland | |
| 1000043799 | Lamb Space Tec GmbH | DE-Germany | Company | No | Alumnus | ESA BIC North Rhine-Westphalia | |
| 1000032433 | Lanterne LTD | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000051100 | LARABICUS GmbH | DE-Germany | Company | Yes | Incubatee | ESA BIC Hessen | |
| 1000043896 | LaterationXYZ GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000041078 | LATITUDE | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000032536 | Latitudo40 S.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000047918 | LAUNCHERSCANNER SRL | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000041359 | LEAGUES GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000044907 | LEAM Technologies GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000042717 | Leasi AS | NO-Norway | Company | Yes | Alumnus | ESA BIC Norway | |
| 1000045668 | Lederer Peter Dipl.-Ing. | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000046242 | leitspalt GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC North Rhine-Westphalia | |
| 1000042393 | lemvos GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000042667 | LEOBLUE | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000048968 | Lepto GmbH | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000043583 | LETO SPACE GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |
| 1000032288 | Let's Earth s.r.o. | CZ-Czech Republic | Company | No | Alumnus | ESA BIC Czech Republic | |