| 1000045141 | LogBook AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000047260 | Lokahi Technology Systems FlexCo | AT-Austria | Company | Yes | Incubatee | ESA BIC Austria | |
| 1000045830 | LOKI s.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000044240 | LOKORA GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000033894 | L-One Systems GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000042807 | LTU Tech | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000043866 | Ludifica srl | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000031799 | Luminovo GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000034722 | Lumiphase | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000045700 | Luna Space Ltd | HU-Hungary | Company | No | Alumnus | ESA BIC Hungary | |
| 1000036465 | Lunar Resources Registry UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000038594 | Lunasa Ltd. | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000031187 | LuxFlux GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000039513 | Lympik GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |
| 1000045578 | MAAGM | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000026622 | Madrid Space Europe S.L. | ES-Spain | Company | Yes | Alumnus | ESA BIC Madrid Region | |
| 1000032837 | Magdrive | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000034159 | MAGMA TECHNOLOGY | FR-France | Company | No | Alumnus | ESA BIC Nord France | |
| 1000048408 | Magnetic Future S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000047000 | magnorobocell GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |