| 1000039625 | Blackpin GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden-Württemberg | |
| 1000016283 | BLACKSHORE B.V. | NL-Netherlands | Company | Yes | Alumnus | ESA BIC Noordwijk | |
| 1000027748 | Blackwave GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000050073 | Blue Neptune International Ltd | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000017739 | BLUE THREAD SRL | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |
| 1000019227 | BLUECOVER TECHNOLOGIES, LDA | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000044805 | BlueZ C Institute - Asssociação para a conservação marinha e economia do carbono | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000037258 | boltzplatz - numerical plasma dynamics GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden-Württemberg | |
| 1000021469 | B-OPEN SOLUTIONS SRL | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000032681 | Boscalia Technologies, S.L | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |
| 1000039381 | Bota Systems AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000044620 | Botronics | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000044928 | Breaby GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000041639 | BSc Max Aragon Cerecedes | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000042431 | BTRY AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000040372 | BWI SAS | FR-France | Company | Yes | Alumnus | ESA BIC Sud France | |
| 1000048247 | Byte2Bit ApS | DK-Denmark | Company | No | Incubatee | ESA BIC Denmark | |
| 1000026569 | Cadami GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000041164 | CAIUS E.E. | GR-Greece | Company | No | Alumnus | ESA BIC Greece | |
| 1000031818 | CANARD DRONES SL | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |