| 1000047798 | LEXION Ι Κ Ε | GR-Greece | Company | No | Incubatee | ESA BIC Greece | |
| 1000041807 | LIDAX ELECTRO-OPTICAL SYSTEMS S.L. | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |
| 1000040861 | lifeline | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000026860 | LIGENTEC | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000038492 | LightCode Photonics | EE-Estonia | Company | No | Alumnus | ESA BIC Estonia | |
| 1000046738 | Lightnovo ApS | DK-Denmark | Company | No | Alumnus | ESA BIC Denmark | |
| 1000045431 | limknow GmbH & Co. KG | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000047387 | LINK2AI GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |
| 1000045064 | LirOptic Limited | IE-Ireland | Company | No | Alumnus | ESA BIC Ireland | |
| 1000044240 | LOKORA GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000033894 | L-One Systems GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000042807 | LTU Tech | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000043866 | Ludifica srl | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000031799 | Luminovo GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000034722 | Lumiphase | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000045700 | Luna Space Ltd | HU-Hungary | Company | No | Alumnus | ESA BIC Hungary | |
| 1000038594 | Lunasa Ltd. | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000031187 | LuxFlux GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000032837 | Magdrive | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000034159 | MAGMA TECHNOLOGY | FR-France | Company | No | Alumnus | ESA BIC Nord France | |