| 1000040613 | SunPlower Propeller GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000028693 | SunReign Ltd | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000041474 | SUNWELL | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000042909 | Supercluster Sp. z o.o. | PL-Poland | Company | No | Alumnus | ESA BIC Poland | |
| 1000049566 | SuperVision Alliance | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000042274 | Surplusmap AS | NO-Norway | Company | No | Alumnus | ESA BIC Norway | |
| 1000026758 | Survey Lab | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |
| 1000042775 | SURVIOT Monitoring Mérnöki Szolgáltató Korlátolt Felelősségű Társaság | HU-Hungary | Company | No | Alumnus | ESA BIC Hungary | |
| 1000048823 | SustainStruct | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |
| 1000033592 | Swarm Logistics GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000041400 | Swistor SA | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000043413 | Sylva AI | FR-France | Company | No | Alumnus | ESA BIC Nord France | |
| 1000041849 | Sylva Germany UG | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000043149 | Symphera GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000040450 | Synchropal srl | IT-Italy | Company | No | Alumnus | ESA BIC Turin | |
| 1000042145 | syrenna | NO-Norway | Company | No | Alumnus | ESA BIC Norway | |
| 1000046530 | Tchombe Entertainment Ltd | GB-United Kingdom | Company | No | Incubatee | ESA BIC UK | |
| 1000037759 | Team Tumbleweed Forschungs OG | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000035363 | TELLUX | FR-France | Company | No | Alumnus | ESA BIC Nord France | |
| 1000042983 | Tenics Software Engineering GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Northern Germany | |