| 1000030044 | OMANOS ANALYTICS | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000032989 | Ommatidia Lidar S.L. | ES-Spain | Company | Yes | Alumnus | ESA BIC Madrid Region | |
| 1000027054 | OPT ALM | FR-France | Company | Yes | Alumnus | ESA BIC Sud France | |
| 1000030217 | OPT/NET BV | NL-Netherlands | Company | Yes | Alumnus | ESA BIC Noordwijk | |
| 1000029654 | Orbital Astronautics | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000042990 | Orbital Matter Poland Sp. z o.o. | PL-Poland | Company | Yes | Alumnus | ESA BIC Poland | |
| 1000043214 | Orbital Paradigm | ES-Spain | Company | Yes | Incubatee | ESA BIC Madrid Region | |
| 1000031454 | OroraTech GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000042598 | OSMIUM ITALY S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000040699 | OXO Earth Technologies UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000032578 | PandionAI AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |
| 1000030875 | Pangea Aerospace S.L. | ES-Spain | Company | Yes | Alumnus | ESA BIC Sud France | |
| 1000037326 | Panopterra UG (haftungsbeschraenkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000043579 | ParaLoon BV | BE-Belgium | Company | Yes | Alumnus | ESA BIC Belgium | |
| 1000038468 | Parametry UG (haftungsbeschränkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000045109 | PARSEC Europe AB | SE-Sweden | Company | Yes | Incubatee | ESA BIC Sweden | |
| 1000032472 | PASQ AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |
| 1000042076 | PAVE Space SA | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000047597 | PeaceEye FlexCo | AT-Austria | Company | Yes | Incubatee | ESA BIC Austria | |
| 1000040669 | PERIGEE GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |