| 1000039520 | Solar Foods | FI-Finland | Company | Yes | Alumnus | ESA BIC Finland | |
| 1000036328 | Solenix Engineering GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000045953 | SOLIDKOSMOS S.A. | GR-Greece | Company | Yes | Incubatee | ESA BIC Greece | |
| 1000041650 | Solmeyea | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000038783 | Sorair Technologies LTD | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000025510 | Space Apps Kft. | HU-Hungary | Company | Yes | Alumnus | ESA BIC Hungary | |
| 1000027974 | Space Composite Structures DENMARK | DK-Denmark | Company | Yes | Alumnus | ESA BIC Denmark | |
| 1000039942 | SPACE DIMENSIONALLY OPTIMIZED TECHNOLOGY SATELLITES LTD - Space DOTS Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000034431 | Space For Life srl | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000041457 | Space Innovation Solutions | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000044422 | SPACE MOBILITY PC - Development of Advanced Mobile Robots | GR-Greece | Company | Yes | Incubatee | ESA BIC Greece | |
| 1000041339 | Space V srl | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000040044 | SpaceABC Kft. | HU-Hungary | Company | Yes | Alumnus | ESA BIC Hungary | |
| 1000041730 | Space-Fit Kft. | HU-Hungary | Company | Yes | Alumnus | ESA BIC Hungary | |
| 1000023439 | SPACEIT OÜ | EE-Estonia | Company | Yes | Alumnus | ESA BIC Estonia | |
| 1000029553 | Space-Lock GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |
| 1000032089 | Spacemanic CZ s.r.o. | CZ-Czech Republic | Company | Yes | Alumnus | ESA BIC Czech Republic | |
| 1000026069 | SPACEMEDEX | FR-France | Company | Yes | Alumnus | ESA BIC Sud France | |
| 1000026584 | Spacenus GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000042701 | Spaceo Lda. | PT-Portugal | Company | Yes | Incubatee | ESA BIC Portugal | |