| 1000045295 | IMENSUS UG (haftungsbeschränkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden-Württemberg | |
| 1000050984 | Infinect Limited | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000047509 | InfiniNode Technologies AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |
| 1000042809 | Infraprint ltd | IE-Ireland | Company | Yes | Alumnus | ESA BIC Ireland | |
| 1000040131 | INSIGHIO P.C. | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000044654 | InSpacePropulsion Technologies GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden-Württemberg | |
| 1000044201 | INSPECTIONDRONE SRL | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000051257 | INSTRUMENTOS ROBOTICOS E INTELIGENCIA ARTIFICIAL S.L. | ES-Spain | Company | Yes | Incubatee | ESA BIC Castilla y Leon | |
| 1000020495 | Integricom Hungary Korlátolt Felelősségű Társasá | HU-Hungary | Company | Yes | Incubatee | ESA BIC Hungary | |
| 1000042371 | Inverto Earth AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000042887 | Involve Space S.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000047313 | IONION S.R.L. | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000047692 | IPAZIASPACE SRL | IT-Italy | Company | Yes | Incubatee | ESA BIC Turin | |
| 1000042854 | Jsio | PT-Portugal | Company | Yes | Alumnus | ESA BIC Portugal | |
| 1000050113 | K2 Photonics AG | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000046155 | Kacadu Corp s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |
| 1000047399 | KAMAHU | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000023616 | KAPPAZETA LTD | EE-Estonia | Company | Yes | Alumnus | ESA BIC Estonia | |
| 1000049439 | KAR Architects LTD | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000047632 | KARL Irrigation AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |