| 1000048968 | Lepto GmbH | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000043583 | LETO SPACE GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |
| 1000048539 | LEVEL ELEVEN STUDIO, MB | LT-Lithuania | Company | Yes | Alumnus | ESA BIC Lithuania | |
| 1000030337 | LIFT ME OFF LIMITED | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000041119 | LIFTERO S.A. | PL-Poland | Company | Yes | Alumnus | ESA BIC Poland | |
| 1000045104 | Lightigo Space s.a.r.l. | LU-Luxembourg | Company | Yes | Alumnus | ESRIC Start-up Support Programme | |
| 1000035890 | Lightly AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000042721 | Linking Drones UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000032753 | LIQUIFER Space Systems GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Northern Germany | |
| 1000033953 | Loctio P.C. | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000041160 | Lodestar Space Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000045141 | LogBook AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000047260 | Lokahi Technology Systems FlexCo | AT-Austria | Company | Yes | Incubatee | ESA BIC Austria | |
| 1000045830 | LOKI s.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000036465 | Lunar Resources Registry UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000039513 | Lympik GmbH | AT-Austria | Company | Yes | Alumnus | ESA BIC Austria | |
| 1000045578 | MAAGM | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000026622 | Madrid Space Europe S.L. | ES-Spain | Company | Yes | Alumnus | ESA BIC Madrid Region | |
| 1000048408 | Magnetic Future S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000048482 | Malnus s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |