| 1000024861 | Open Cosmos Ltd. | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000029654 | Orbital Astronautics | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000042990 | Orbital Matter Poland Sp. z o.o. | PL-Poland | Company | Yes | Alumnus | ESA BIC Poland | |
| 1000043214 | Orbital Paradigm | ES-Spain | Company | Yes | Alumnus | ESA BIC Madrid Region | |
| 1000043764 | O-Robotics ApS | DK-Denmark | Company | Yes | Alumnus | ESA BIC Denmark | |
| 1000031454 | OroraTech GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000042598 | OSMIUM ITALY S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000046288 | Osmos X | FR-France | Company | Yes | Incubatee | ESA BIC Nord France | |
| 1000036590 | OUR WATCH LEADS - OWL, LDA | PT-Portugal | Company | Yes | Alumnus | ESA BIC Portugal | |
| 1000045503 | Oxford RF Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000040699 | OXO Earth Technologies GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000047135 | PACK AWAY | SE-Sweden | Company | Yes | Incubatee | ESA BIC Sweden | |
| 1000050640 | Paladin Space Ltd | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000031523 | Panda Insight UG (haftungsbeschrankt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000032578 | PandionAI AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |
| 1000030875 | Pangea Aerospace S.L. | ES-Spain | Company | Yes | Alumnus | ESA BIC Sud France | |
| 1000037326 | Panopterra UG (haftungsbeschraenkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000043579 | ParaLoon BV | BE-Belgium | Company | Yes | Alumnus | ESA BIC Belgium | |
| 1000038468 | Parametry UG (haftungsbeschränkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000045109 | PARSEC Europe AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |