| 1000045042 | Ricardo, Domingos & Bergano, Lda | PT-Portugal | Company | Yes | Alumnus | ESA BIC Portugal | |
| 1000042772 | RIDE | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000044093 | Right Step OÜ | EE-Estonia | Company | Yes | Alumnus | ESA BIC Estonia | |
| 1000049486 | Rimti Išvien | LT-Lithuania | Company | Yes | Incubatee | ESA BIC Lithuania | |
| 1000048519 | Rosa Earth SAS | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000046564 | ROUTEZERO LTD | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000045169 | Rubicon Exploration | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000040428 | S&T ITALY S.R.L. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000039325 | S2G Technologies | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000044441 | SAGA Studio ApS | DK-Denmark | Company | Yes | Alumnus | ESA BIC Denmark | |
| 1000046714 | SAIF Systems Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000046089 | SaltLines Geo Limited | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000041471 | Salutes Space UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000042743 | Samudra Oceans Limited | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000050616 | SAR Metrics PSA | PL-Poland | Company | Yes | Incubatee | ESA BIC Poland | |
| 1000045771 | SAR Projects MB | LT-Lithuania | Company | Yes | Alumnus | ESA BIC Lithuania | |
| 1000036881 | satsearch holding B.V. - blocked | NL-Netherlands | Company | Yes | Alumnus | ESA BIC Noordwijk | |
| 1000034833 | SCALE Nanotech | EE-Estonia | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000045772 | Scanio Technologies Unipessoal Lda. | PT-Portugal | Company | Yes | Alumnus | ESA BIC Portugal | |
| 1000033963 | SCouP | BE-Belgium | Company | Yes | Alumnus | ESA BIC Belgium | |