| 1000051732 | Odes Space P.C. | GR-Greece | Company | No | Incubatee | ESA BIC Greece | |
| 1000040618 | Odonata GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000043081 | Officina REV srl | IT-Italy | Company | No | Alumnus | ESA BIC Turin | |
| 1000046769 | Oinride Oy | FI-Finland | Company | No | Alumnus | ESA BIC Finland | |
| 1000042494 | Okeanos Smart Data Solutions GmbH | DE-Germany | Company | No | Alumnus | ESA BIC North Rhine-Westphalia | |
| 1000042424 | Olive Robotics GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000027054 | OPT ALM | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000044838 | Optocycle GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000042239 | OPUS Aerospace | FR-France | Company | No | Alumnus | ESA BIC Nord France | |
| 1000030848 | ORBITAL CARGO DRONE LTD | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000040177 | Orbital Outpost Italy S.R.L. | IT-Italy | Company | No | Alumnus | ESA BIC Turin | |
| 1000029399 | Orbital Witness Limited | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000044988 | Oris | IT-Italy | Company | No | Alumnus | ESA BIC Turin | |
| 1000045195 | Oshen Ltd | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000031502 | OXFORD EARTH OBSERVATION LIMITED | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000026419 | Oxiway Ltd | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000048587 | PENGUINBIO GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |
| 1000040669 | PERIGEE GmbH | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000035607 | Permagro | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000047436 | Perovskia Solar AG | CH-Switzerland | Company | No | Incubatee | ESA BIC Switzerland | |