| 1000043502 | UDX s.r.o. | CZ-Czech Republic | Company | No | Alumnus | ESA BIC Czech Republic | |
| 1000036466 | Ultima Forma Ltd | GB-United Kingdom | Company | No | Alumnus | ESA BIC UK | |
| 1000045024 | umbrella space science ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000037958 | Uneeqly s.r.o. | CZ-Czech Republic | Company | No | Alumnus | ESA BIC Czech Republic | |
| 1000024199 | UNIBAP AB | SE-Sweden | Company | Yes | Alumnus | ESA BIC Sweden | |
| 1000028140 | Unisphere GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000046188 | UniteLabs GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000043683 | UNIVITY | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000041513 | Unleash Future Boats | DE-Germany | Company | No | Alumnus | ESA BIC Northern Germany | |
| 1000043438 | Unmanned Dynamics UAB | LT-Lithuania | Company | No | Alumnus | ESA BIC Lithuania | |
| 1000037693 | Unmanned Technical Works S.L.L. | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |
| 1000039044 | UNSEENLABS | FR-France | Company | Yes | Alumnus | ESA BIC Nord France | |
| 1000041825 | UP Catalyst OÜ | EE-Estonia | Company | Yes | Alumnus | ESA BIC Estonia | |
| 1000036916 | Upteko | DK-Denmark | Company | No | Alumnus | ESA BIC Denmark | |
| 1000029690 | Uptimai s.r.o. | CZ-Czech Republic | Company | Yes | Alumnus | ESA BIC Czech Republic | |
| 1000031590 | UptoEarth | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000039821 | Urban Ray GmbH | DE-Germany | Company | No | Alumnus | ESA BIC North Rhine-Westphalia | |
| 1000039475 | UrbanDataLab AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000043665 | UrbanSens UG (Haftungsbeschränkt) | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000027910 | UrbyetOrbit srls | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |