| 1000051905 | ECLIPSE | FR-France | Company | No | Incubatee | ESA BIC Nord France | |
| 1000038338 | egsespace s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |
| 1000046299 | Einbus Oy | FI-Finland | Company | Yes | Incubatee | ESA BIC Finland | |
| 1000048283 | EM Path | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000047413 | Embed-Rover | PL-Poland | Company | Yes | Incubatee | ESA BIC Poland | |
| 1000046360 | EMBEREYE LTD | GB-United Kingdom | Company | No | Incubatee | ESA BIC UK | |
| 1000050313 | Embodied AI SA | CH-Switzerland | Company | Yes | Incubatee | ESA BIC Switzerland | |
| 1000050817 | Emissium SA | CH-Switzerland | Company | No | Incubatee | ESA BIC Switzerland | |
| 1000049941 | empiriQa | PL-Poland | Company | Yes | Incubatee | ESA BIC Poland | |
| 1000037711 | Enovus Labs Ltd | IE-Ireland | Company | Yes | Incubatee | ESA BIC Ireland | |
| 1000050145 | Enwave P.S.A. | PL-Poland | Company | No | Incubatee | ESA BIC Poland | |
| 1000049639 | Eos Space Technology | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |
| 1000047739 | Epona AI Labs Limited | IE-Ireland | Company | Yes | Incubatee | ESA BIC Ireland | |
| 1000049752 | EquaFish AS | NO-Norway | Company | Yes | Incubatee | ESA BIC Norway | |
| 1000049807 | EWIA.tech Unternehmergesellschaft (haftungsbeschraenkt) | DE-Germany | Company | No | Incubatee | ESA BIC Hessen | |
| 1000048834 | ExoGen Space s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |
| 1000052532 | EXOVIRO sp. z o.o. (Ltd.) | PL-Poland | Company | Yes | Incubatee | ESA BIC Poland | |
| 1000050354 | FID Avionics s.r.o. | CZ-Czech Republic | Company | Yes | Incubatee | ESA BIC Czech Republic | |
| 1000049670 | FLIPoQ GmbH | DE-Germany | Company | Yes | Incubatee | ESA BIC Hessen | |
| 1000048205 | Fusion Dynamics Corporation Ltd | GB-United Kingdom | Company | Yes | Incubatee | ESA BIC UK | |