| 1000040861 | lifeline | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |
| 1000030337 | LIFT ME OFF LIMITED | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000041119 | LIFTERO S.A. | PL-Poland | Company | Yes | Alumnus | ESA BIC Poland | |
| 1000026860 | LIGENTEC | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000038492 | LightCode Photonics | EE-Estonia | Company | No | Alumnus | ESA BIC Estonia | |
| 1000045104 | Lightigo Space s.a.r.l. | LU-Luxembourg | Company | Yes | Alumnus | ESRIC Start-up Support Programme | |
| 1000035890 | Lightly AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000046738 | Lightnovo ApS | DK-Denmark | Company | No | Alumnus | ESA BIC Denmark | |
| 1000045431 | limknow GmbH & Co. KG | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000042721 | Linking Drones UG | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000032753 | LIQUIFER Space Systems GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Northern Germany | |
| 1000045064 | LirOptic Limited | IE-Ireland | Company | No | Alumnus | ESA BIC Ireland | |
| 1000033953 | Loctio P.C. | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000041160 | Lodestar Space Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000045141 | LogBook AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000045830 | LOKI s.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Turin | |
| 1000044240 | LOKORA GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden-Württemberg | |
| 1000033894 | L-One Systems GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000042807 | LTU Tech | FR-France | Company | No | Alumnus | ESA BIC Sud France | |
| 1000043866 | Ludifica srl | BE-Belgium | Company | No | Alumnus | ESA BIC Belgium | |