| 1000034899 | Bareways GmbH | DE-Germany | Company | No | Incubatee | ESA BIC Northern Germany | |
| 1000046350 | Be MarS Aps | DK-Denmark | Company | Yes | Incubatee | ESA BIC Denmark | |
| 1000040165 | Beetle ForTech | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000033765 | Benenati & Edwards GbR | DE-Germany | Company | No | Alumnus | ESA BIC Baden Württemberg | |
| 1000036644 | BestHealth4U | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000040994 | BETADYNAMIQ S.R.L. | IT-Italy | Company | Yes | Incubatee | ESA BIC Lazio | |
| 1000030473 | Big Terra Alpha | CZ-Czech Republic | Company | Yes | Alumnus | ESA BIC Czech Republic | |
| 1000043139 | BIOORBIT LTD | GB-United Kingdom | Company | No | Incubatee | ESA BIC UK | |
| 1000045466 | BIOTA MRV LTD | IE-Ireland | Company | No | Incubatee | ESA BIC Ireland | |
| 1000039610 | Bitrezus P.C. | GR-Greece | Company | Yes | Alumnus | ESA BIC Greece | |
| 1000033967 | Black Engine Aerospace GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden Württemberg | |
| 1000039625 | Blackpin GmbH | DE-Germany | Company | No | Alumnus | ESA BIC Baden Württemberg | |
| 1000016283 | BLACKSHORE B.V. | NL-Netherlands | Company | Yes | Alumnus | ESA BIC Noordwijk | |
| 1000027748 | Blackwave GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000017739 | BLUE THREAD SRL | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |
| 1000019227 | BLUECOVER TECHNOLOGIES, LDA | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000044805 | BlueZ C Institute - Asssociação para a conservação marinha e economia do carbono | PT-Portugal | Company | No | Incubatee | ESA BIC Portugal | |
| 1000037258 | boltzplatz - numerical plasma dynamics GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden Württemberg | |
| 1000021469 | B-OPEN SOLUTIONS SRL | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000032681 | Boscalia Technologies, S.L | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |