| 1000031983 | Dynamic Space Technologies AS | NO-Norway | Company | No | Alumnus | ESA BIC Norway | |
| 1000041734 | Ecosmic | NL-Netherlands | Company | No | Incubatee | ESA BIC Noordwijk | |
| 1000031159 | EH Group Engineering AG | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000036979 | Ekofolio Sarl | LU-Luxembourg | Company | No | Alumnus | ESA BIC Denmark | |
| 1000028372 | ElFys Oy | FI-Finland | Company | Yes | Alumnus | ESA BIC Finland | |
| 1000037443 | Elysium Industries UG | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000021377 | EMBOTECH AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000023388 | EMTECH GMBH | DE-Germany | Company | No | Alumnus | ESA BIC Hessen | |
| 1000041182 | ENANTIOS | CH-Switzerland | Company | No | Incubatee | ESA BIC Switzerland | |
| 1000038978 | Enernite AS | NO-Norway | Company | Yes | Alumnus | ESA BIC Norway | |
| 1000030984 | Engineering Minds Munich GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000028618 | Enlightra SARL | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000029559 | Eptune Engineering Lda. | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000042695 | ESG Solutions & Consulting GmbH | AT-Austria | Company | Yes | Incubatee | ESA BIC Austria | |
| 1000035077 | Estimo-GNSS | EE-Estonia | Company | No | Alumnus | ESA BIC Estonia | |
| 1000039473 | EULA IT GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Bavaria | |
| 1000042829 | Extremo Technologies | PL-Poland | Company | Yes | Incubatee | ESA BIC Poland | |
| 1000037446 | Falconers | EE-Estonia | Company | No | Incubatee | ESA BIC Estonia | |
| 1000039211 | Fauna Smart Technologies ApS | DK-Denmark | Company | Yes | Alumnus | ESA BIC Denmark | |
| 1000037040 | Fixposition AG | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |