| 1000027465 | ColomboSky s.r.l. | IT-Italy | Company | No | Alumnus | ESA BIC Lazio | |
| 1000038069 | CompPair Technologies Ltd | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000039220 | condenZero | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000034538 | Connect Robotics (CRSA - Connect Robotics Sistemas Autónomos, Lda.) | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |
| 1000035883 | ConstellR GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Baden Württemberg | |
| 1000045176 | Coolx Earth S.L | ES-Spain | Company | No | Alumnus | ESA BIC Madrid Region | |
| 1000035240 | CORAmaps GmbH | DE-Germany | Company | Yes | Alumnus | ESA BIC Hessen | |
| 1000039329 | Corintis SA | CH-Switzerland | Company | No | Alumnus | ESA BIC Switzerland | |
| 1000039489 | Correntics GmbH | CH-Switzerland | Company | Yes | Alumnus | ESA BIC Switzerland | |
| 1000037164 | Cosmic S.r.l. | IT-Italy | Company | Yes | Alumnus | ESA BIC Lazio | |
| 1000046153 | cosy.green GmbH | DE-Germany | Company | Yes | Incubatee | ESA BIC Hessen | |
| 1000028834 | CropOM | AT-Austria | Company | No | Alumnus | ESA BIC Austria | |
| 1000040580 | CropOM-Hungary Kft. | HU-Hungary | Company | Yes | Alumnus | ESA BIC Hungary | |
| 1000037108 | Crover Ltd | GB-United Kingdom | Company | Yes | Alumnus | ESA BIC UK | |
| 1000018471 | CRYSTALSPACE OÜ | EE-Estonia | Company | Yes | Alumnus | ESA BIC Estonia | |
| 1000041412 | CSHARK SRL | IT-Italy | Company | No | Incubatee | ESA BIC Lazio | |
| 1000042115 | CSTREAM UG | DE-Germany | Company | No | Alumnus | ESA BIC Bavaria | |
| 1000045304 | Cstrider AB | SE-Sweden | Company | No | Incubatee | ESA BIC Sweden | |
| 1000044717 | Curf | BE-Belgium | Company | Yes | Alumnus | ESA BIC Belgium | |
| 1000031834 | CybELE LAWGICAL LDA | PT-Portugal | Company | No | Alumnus | ESA BIC Portugal | |